Comprehensive in vitro and in silico analysis of Piliostigma thonningii’s bioactive compounds as multifunctional inhibitors of α-amylase, α-glucosidase, and oxidative stress for enhanced glycemic regulation

Type 2 diabetes mellitus is a growing global health crisis requiring effective management strategies, including the control of postprandial hyperglycemia. Inhibiting key carbohydrate-digesting enzymes, namely α-amylase and α-glucosidase, is a proven therapeutic approach. However, many current inhibi...

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Principais autores:	Alfred Sisinvou, Honoré Wangso, Hamadou Mamoudou, Sali Mouhamadou, Benoît Bargui Koubala, Mohamed F. AlAjmi, Celine Henoumont, Sophie Laurent, Mohit Agrawal, Emmanuel Talla
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-12-01
coleção:	The Microbe
Assuntos:	Piliostigma thonningii α-amylase inhibitors α-glucosidase inhibitors type 2 diabetes molecular docking molecular dynamics simulations
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2950194625003930
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