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Early immune response to Coccidioides is characterized by robust neutrophil and fibrotic macrophage recruitment and differentiation

ABSTRACT Coccidioidomycosis, or Valley fever, is an emerging respiratory disease caused by soil-dwelling fungi of the Coccidioides genus that is expected to spread from the southwest into the central U.S. by 2050. While 60% of infections are asymptomatic, the other 40% of patients experience a range...

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Principais autores: Nadia Miranda, Oscar A. Davalos, Aimy Sebastian, Margarita V. Rangel, Nicole F. Leon, Bria M. Gorman, Deepa K. Murugesh, Nicholas R. Hum, Gabriela G. Loots, Katrina K. Hoyer, Dina R. Weilhammer
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2025-09-01
Serier:Microbiology Spectrum
Fag:
Coccidioides
scRNAseq
neutrophils
macrophages
Valley fever
Online adgang:https://journals.asm.org/doi/10.1128/spectrum.00442-25
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