Microneedles integrated with crystallinity control for poorly water-soluble drugs: Enhanced bioavailability and innovative controlled release system

The purpose of this study was to develop innovative microneedles with drug crystallinity control for the fast or sustained release of poorly water-soluble drugs. Povidone was determined as a suitable polymer following hydrophilic polymer testing using solubilization screening technique. Microneedles...

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Autori principali:	Mi Ran Woo, Jung Suk Kim, Seunghyun Cheon, Sang Hun Ji, Seonghyeon Park, Sanghyun Woo, Jong Oh Kim, Sung Giu Jin, Han-Gon Choi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2024-11-01
Serie:	Materials & Design
Soggetti:	Microneedle Drug crystallinity Mechanical properties Release Skin permeability Transdermal drug delivery
Accesso online:	http://www.sciencedirect.com/science/article/pii/S0264127524007469
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