Maternal N-Acetylcysteine Therapy Prevents Hypertension in Spontaneously Hypertensive Rat Offspring: Implications of Hydrogen Sulfide-Generating Pathway and Gut Microbiota

Hypertension can come from early life. N-acetylcysteine (NAC), a hydrogen sulfide (H₂S) precursor as well as an antioxidant, has antihypertensive effect. We investigated whether maternal NAC therapy can protect spontaneously hypertensive rats (SHR) male offspring against hypertension. The...

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Detalhes bibliográficos

Principais autores:	Chien-Ning Hsu, Chih-Yao Hou, Guo-Ping Chang-Chien, Sufan Lin, You-Lin Tain
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-09-01
coleção:	Antioxidants
Assuntos:	developmental origins of health and disease (DOHaD) gut microbiota hydrogen sulfide hypertension N-acetylcysteine oxidative stress
Acesso em linha:	https://www.mdpi.com/2076-3921/9/9/856
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