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4‐Aminopyridine promotes functional recovery and remyelination in acute peripheral nerve injury

Abstract Traumatic peripheral nerve damage is a major medical problem without effective treatment options. In repurposing studies on 4‐aminopyridine (4‐AP), a potassium channel blocker that provides symptomatic relief in some chronic neurological afflictions, we discovered this agent offers signific...

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Autors principals: Kuang‐Ching Tseng, Haiyan Li, Andrew Clark, Leigh Sundem, Michael Zuscik, Mark Noble, John Elfar
Format: Artigo
Idioma:Inglês
Publicat: Springer Nature 2016-11-01
Col·lecció:EMBO Molecular Medicine
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Accés en línia:https://doi.org/10.15252/emmm.201506035
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