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Cell Death Induction and Protection by Activation of Ubiquitously Expressed Anion/Cation Channels. Part 1: Roles of VSOR/VRAC in Cell Volume Regulation, Release of Double-Edged Signals and Apoptotic/Necrotic Cell Death

Cell volume regulation (CVR) is essential for survival and functions of animal cells. Actually, normotonic cell shrinkage and swelling are coupled to apoptotic and necrotic cell death and thus called the apoptotic volume decrease (AVD) and the necrotic volume increase (NVI), respectively. A number o...

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Principais autores: Yasunobu Okada, Ravshan Z. Sabirov, Kaori Sato-Numata, Tomohiro Numata
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-01-01
coleção:Frontiers in Cell and Developmental Biology
Assuntos:
cell volume regulation
apoptotic cell death
necrotic cell death
VSOR/VRAC
glutamate release
GSH release
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fcell.2020.614040/full
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