Performance of Composite Endpoints Defining Progression Independent of Relapse Activity in Multiple Sclerosis

ABSTRACT Objective The characteristics and utility of composite progression independent of relapse activity (cPIRA; worsening on the Expanded Disability Status Scale [EDSS], or 9‐Hole Peg Test, or Timed 25‐Foot Walk Test) were evaluated as an endpoint in relapsing multiple sclerosis (RMS) trials usi...

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Detalles Bibliográficos

Principais autores:	Ludwig Kappos, Sean Yiu, Jason Reucassel, Jiwon Oh, Cristina Granziera, Joep Killestein, Robert A. Bermel, Claude Berge, Agne Kazlauskaite, Hans‐Martin Schneble, Frank Dahlke, Bruce A. C. Cree
Formato:	Artigo
Idioma:	Inglês
Publicado:	Wiley 2025-09-01
Series:	Annals of Clinical and Translational Neurology
Assuntos:	clinical trial disability progression multiple sclerosis progression independent of relapse activity
Acceso en liña:	https://doi.org/10.1002/acn3.70111
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