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p63 and p53: Collaborative Partners or Dueling Rivals?

The tumor suppressor p53 and its oncogenic sibling p63 (ΔNp63) direct opposing fates in tumor development. These paralog proteins are transcription factors that elicit their tumor suppressive and oncogenic capacity through the regulation of both shared and unique target genes. Both proteins predomin...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dana L. Woodstock, Morgan A. Sammons, Martin Fischer
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2021-07-01
Cyfres:Frontiers in Cell and Developmental Biology
Pynciau:
Mynediad Ar-lein:https://www.frontiersin.org/articles/10.3389/fcell.2021.701986/full
Tagiau: Ychwanegu Tag
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