A large-scale concordance study of toxicity findings across preclinical species and humans for small molecules and biologics
Translating preclinical safety findings into reliable insights for human risk assessment remains a fundamental challenge in drug development. Prior preclinical-clinical concordance studies have been constrained by limited drug coverage, reliance on identical-term matching for adverse events (AEs), a...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2026-04-01
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| Schriftenreihe: | Frontiers in Toxicology |
| Schlagworte: | |
| Online-Zugang: | https://www.frontiersin.org/articles/10.3389/ftox.2026.1731947/full |
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