An operational target trial emulation framework for causal inference using electronic health record data
Abstract Target trial emulation (TTE) enables causal inference from electronic health record (EHR) data when randomized clinical trials are infeasible, but its validity depends on whether EHR data can support the required trial design components. This review presents an operational framework that di...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Portfolio
2026-04-01
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| Schriftenreihe: | npj Digital Medicine |
| Online-Zugang: | https://doi.org/10.1038/s41746-026-02563-z |
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