Cancer stem cells and tumor-associated macrophages as mates in tumor progression: mechanisms of crosstalk and advanced bioinformatic tools to dissect their phenotypes and interaction

Cancer stem cells (CSCs) are a small subset within the tumor mass significantly contributing to cancer progression through dysregulation of various oncogenic pathways, driving tumor growth, chemoresistance and metastasis formation. The aggressive behavior of CSCs is guided by several intracellular s...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Francesco Verona, Sebastiano Di Bella, Roberto Schirano, Camilla Manfredi, Francesca Angeloro, Giulia Bozzari, Matilde Todaro, Giuseppe Giannini, Giorgio Stassi, Veronica Veschi
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Frontiers Media S.A. 2025-02-01
श्रृंखला:	Frontiers in Immunology
विषय:	cancer stem cells TAMs single-cell RNA sequencing (scRNA-seq) spatial transcriptomics signaling pathway analysis trajectory analysis
ऑनलाइन पहुंच:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1529847/full
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