Orexin A protects against cerebral ischemia-reperfusion injury by enhancing reperfusion in ischemic cortex via HIF-1α-ET-1/eNOS pathway

The purpose of this study was to investigate the protective effect and underlying mechanism of orexin A on cerebral ischemia-reperfusion injury, specifically through vasodilation mediated by the hypoxia inducible factor-1α (HIF-1α)-Endothelin-1(ET-1)/endothelial nitric oxide synthase (eNOS) pathway....

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Hlavní autoři:	Minxia Zhu, Xiaofeng Li, Jing Guo, Zhaojun Zhang, Xu Guo, Zhuoqi Li, Junwei Lin, Pengfei Li, Zixuan Jiang, Yifan Zhu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-11-01
Edice:	Brain Research Bulletin
Témata:	Orexin A Cerebral ischemia-reperfusion injury HIF-1α ET-1 eNOS
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S0361923024002399
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