Caveolin-1 Down-Regulation Reduces VEGF-A Secretion Induced by IGF-1 in ARPE-19 Cells

The insulin-like growth factor 1 (IGF-1) stimulates expression and secretion of vascular endothelial growth factor-A (VEGF-A), the main actor in ocular neovascularization, by RPE cells. Activity of IGF-1 is regulated by interaction between its receptor and Caveolin-1 (Cav-1), the main component of c...

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Principais autores:	Alessandra Puddu, Roberta Sanguineti, Davide Maggi
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2021-12-01
Series:	Life
Assuntos:	caveolin-1 vascular endothelial growth factor A insulin-like growth factor-1 ocular neovascularization retinal pigment epithelium endothelial cells
Acceso en liña:	https://www.mdpi.com/2075-1729/12/1/44
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