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Considerations and implications of current in vitro model systems to study optic nerve head cellular mechanobiology

The optic nerve head (ONH) is a primary site of biomechanical strain within the eye. Here, tensile, compressive and shear forces can impact both physiologic function and pathologic dysfunction of the tissue. Under healthy conditions, the ONH can withstand dynamic fluctuations in intraocular pressure...

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Autori principali: Ana N. Strat, Preethi S. Ganapathy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2025-10-01
Serie:Frontiers in Cell and Developmental Biology
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Accesso online:https://www.frontiersin.org/articles/10.3389/fcell.2025.1699793/full
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