Spinal microglia contribute to sustained inflammatory pain via amplifying neuronal activity

Abstract Microglia are highly dynamic immune cells of the central nervous system (CNS). Microglial processes interact with neuronal elements constantly on the order of minutes. The functional significance of this acute microglia-neuron interaction and its potential role in the context of pain is sti...

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Autors principals:	Nan Gu, Min-Hee Yi, Madhuvika Murugan, Manling Xie, Sebastian Parusel, Jiyun Peng, Ukpong B. Eyo, Christine L. Hunt, Hailong Dong, Long-Jun Wu
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2022-10-01
Col·lecció:	Molecular Brain
Matèries:	Microglia Microglia–neuron interaction Inflammatory pain Formalin P2Y12 receptor Two-photon imaging
Accés en línia:	https://doi.org/10.1186/s13041-022-00970-3
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