SARS-CoV-2 Spike Protein 1 Activates Microvascular Endothelial Cells and Complement System Leading to Platelet Aggregation

Microvascular thrombosis is associated with multiorgan failure and mortality in coronavirus disease 2019 (COVID-19). Although thrombotic complications may be ascribed to the ability of SARS-CoV-2 to infect and replicate in endothelial cells, it has been poorly investigated whether, in the complexity...

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Principais autores:	Luca Perico, Marina Morigi, Miriam Galbusera, Anna Pezzotta, Sara Gastoldi, Barbara Imberti, Annalisa Perna, Piero Ruggenenti, Roberta Donadelli, Ariela Benigni, Giuseppe Remuzzi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-03-01
Colecção:	Frontiers in Immunology
Assuntos:	COVID-19 SARS-CoV-2 spike protein 1 complement system endothelial dysfunction inflammation thrombosis
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.827146/full
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