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HJURP inhibits sensitivity to ferroptosis inducers in prostate cancer cells by enhancing the peroxidase activity of PRDX1

Ferroptosis induction has emerged as a promising therapeutic approach for prostate cancer (PCa), either as a monotherapy or in combination with hormone therapy. Therefore, identifying the mechanisms regulating ferroptosis in PCa cells is essential. Our previous study demonstrated that HJURP, an onco...

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Wedi'i Gadw mewn:
Prif Awduron: Wenjie Lai, Weian Zhu, Jianjie Wu, Jiongduan Huang, Xiaojuan Li, Yun Luo, Yu Wang, Hengda Zeng, Mingqiang Li, Xiaofu Qiu, Xingqiao Wen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2024-11-01
Cyfres:Redox Biology
Pynciau:
Prostate cancer
Ferroptosis
HJURP
Peroxidase activity
Disulfide binding
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S2213231724003707
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