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RNA polymerase II transcription attenuation at the yeast DNA repair gene <i>DEF1</i> is biologically significant and dependent on the Hrp1 RNA-recognition motif

AbstractPremature transcription termination (i.e. attenuation) is a potent gene regulatory mechanism that represses mRNA synthesis. Attenuation of RNA polymerase II is more prevalent than once appreciated, targeting 10–15% of mRNA genes in yeast through higher eukaryotes, but its sig...

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Bibliografiske detaljer
Principais autores: Maria E Amodeo, Shane P C Mitchell, Vincent Pavan, Jason N Kuehner
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2022-10-01
Serier:G3: Genes, Genomes, Genetics
Online adgang:https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkac292
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