Identification and Phenotypic Characterization of Hsp90 Phosphorylation Sites That Modulate Virulence Traits in the Major Human Fungal Pathogen Candida albicans

The highly conserved, ubiquitous molecular chaperone Hsp90 is a key regulator of cellular proteostasis and environmental stress responses. In human pathogenic fungi, which kill more than 1.6 million patients each year worldwide, Hsp90 governs cellular morphogenesis, drug resistance, and virulence. Y...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Leenah Alaalm, Julia L. Crunden, Mark Butcher, Ulrike Obst, Ryann Whealy, Carolyn E. Williamson, Heath E. O’Brien, Christiane Schaffitzel, Gordon Ramage, James Spencer, Stephanie Diezmann
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2021-08-01
Serija:	Frontiers in Cellular and Infection Microbiology
Teme:	fungal virulence phospho-switch Hsp90 thermotolerance drug response morphogenesis
Online dostop:	https://www.frontiersin.org/articles/10.3389/fcimb.2021.637836/full
Oznake:	Označite Brez oznak, prvi označite!