Altered memory CCR6+ Th17-polarised T-cell function and biology in people with HIV under successful antiretroviral therapy and HIV elite controllersResearch in context

Summary: Background: Despite successful antiretroviral therapy (ART), frequencies and immunological functions of memory CCR6+ Th17-polarised CD4+ T-cells are not fully restored in people with HIV (PWH). Moreover, long-lived Th17 cells contribute to HIV persistence under ART. However, the molecular...

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主要な著者:	Alexis Yero, Jean-Philippe Goulet, Tao Shi, Cecilia T. Costiniuk, Jean-Pierre Routy, Cecile Tremblay, Ralph-Sydney Mboumba Bouassa, Yulia Alexandrova, Amélie Pagliuzza, Nicolas Chomont, Petronela Ancuta, Mohammad-Ali Jenabian
フォーマット:	Artigo
言語:	Inglês
出版事項:	Elsevier 2024-09-01
シリーズ:	EBioMedicine
主題:	Th17 cells CCR6 HIV infection Transcriptomics HIV persistence DNA damage
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2352396424003104
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