VPS13A is closely associated with mitochondria and is required for efficient lysosomal degradation
Members of the VPS13 family are associated with various human diseases. In particular, the loss of function of VPS13A leads to chorea-acanthocytosis (ChAc), a rare neurodegenerative disease without available curative treatments. Autophagy has been considered a promising therapeutic target because th...
Furkejuvvon:
| Váldodahkkit: | , , , |
|---|---|
| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
The Company of Biologists
2019-02-01
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| Ráidu: | Disease Models & Mechanisms |
| Fáttát: | |
| Liŋkkat: | http://dmm.biologists.org/content/12/2/dmm036681 |
| Fáddágilkorat: |
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