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STING inhibits viral lytic reactivation and cell growth in primary effusion lymphoma

Kaposi’s sarcoma-associated herpesvirus (KSHV) is a DNA virus linked to multiple malignancies associated with compromised immunity, such as Kaposi’s sarcoma (KS) and primary effusion lymphoma (PEL). These malignancies are strongly linked to HIV coinfection and remain major oncogenic risks even with...

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Principais autores: Tiffany S. Nelson, Cathrine Pacini, Amy Nguyen, Travis M. Zeigler, Alexa Ziff, Kimberly Paulsen, Alayna Simpson, Sumita Bhaduri-McIntosh, Zhe Ma
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-05-01
Serier:Frontiers in Immunology
Fag:
agonist
EBV
innate immunity
KSHV
primary effusion lymphoma
STING
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1823240/full
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