Identification of <i>NRAS</i> Downstream Genes with CRISPR Activation Screening

Mutations in <i>NRAS</i> constitutively activate cell proliferation signaling in malignant neoplasms, such as leukemia and melanoma, and the clarification of comprehensive downstream genes of <i>NRAS</i> might lead to the control of cell-proliferative signals of <i>NRAS</i>-driven cancers. We previo...

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Главные авторы:	Akiya Tatsumi, Haruka Hirakochi, Satomi Inoue, Yosuke Tanaka, Hidehiro Furuno, Masumi Ikeda, Sachiko Ishibashi, Towako Taguchi, Kouhei Yamamoto, Iichiroh Onishi, Zohar Sachs, David A. Largaespada, Masanobu Kitagawa, Morito Kurata
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2022-10-01
Серии:	Biology
Предметы:	CRISPR screening NRAS
Online-ссылка:	https://www.mdpi.com/2079-7737/11/11/1551
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