A rhesus macaque intragastric challenge model for evaluating the safety, immunogenicity, and efficacy of live-attenuated Shigella dysenteriae 1 vaccine candidates

Shigellosis remains a significant global health challenge, particularly in Asia and Africa, where it is a major cause of morbidity and mortality among children. Despite the urgent need, the development of a licensed Shigella vaccine has been hindered, partly due to the lack of suitable animal models...

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Hlavní autoři:	Nattaya Ruamsap, Rawiwan Imerbsin, Patchariya Khanijou, Siriphan Gonwong, Wilawan Oransathit, Shoshana Barnoy, Malabi M. Venkatesan, Sidhartha Chaudhury, Dilara Islam
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-09-01
Edice:	Frontiers in Microbiology
Témata:	Shigella dysenteriae 1 WRSd1 WRSd2 WRSd3 WRSd4 WRSd5
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fmicb.2024.1454338/full
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