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Case Study: HLA incompatible platelet infusion to allow emergency salvage HCT in a patient with primary graft failure due to donor specific HLA antibody

A patient with myelodysplasia received a haploidentical hematopoietic stem cell transplant (HCT). Pre-transplant HLA antibody screening showed no detectable donor-specific antibodies (DSAs). Post-transplant, the patient developed an anti-HLA-A2 antibody, likely due to a memory B-cell response. This...

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Principais autores: Louise Goddard, Jonathan Moses, Gerard Joseph Chu, Robert P. Carroll
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2026-02-01
סדרה:Frontiers in Immunology
נושאים:
donor specific antibody
infusion
platelet
refractoriness
stem cell transplantation
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1752791/full
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