Coupled pre‐mRNA and mRNA dynamics unveil operational strategies underlying transcriptional responses to stimuli

Abstract Transcriptional responses to extracellular stimuli involve tuning the rates of transcript production and degradation. Here, we show that the time‐dependent profiles of these rates can be inferred from simultaneous measurements of precursor mRNA (pre‐mRNA) and mature mRNA profiles. Transcrip...

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Dades bibliogràfiques

Autors principals:	Amit Zeisel, Wolfgang J Köstler, Natali Molotski, Jonathan M Tsai, Rita Krauthgamer, Jasmine Jacob‐Hirsch, Gideon Rechavi, Yoav Soen, Steffen Jung, Yosef Yarden, Eytan Domany
Format:	Artigo
Idioma:	Inglês
Publicat:	Springer Nature 2011-09-01
Col·lecció:	Molecular Systems Biology
Matèries:	half‐life operational strategy pre‐mRNA transcriptional response
Accés en línia:	https://doi.org/10.1038/msb.2011.62
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