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Down-regulation of FGF10 in hypospadias prepuce associated with severity

Background: Fibroblast growth factors (FGF) expressed in the genital tubercle, especially FGF8 and FGF10, may be implicated in the morphogenesis of external genitalia. We investigated the expression of FGF8 and FGF10 in hypospadias prepuce to confirm any correlation. Methods: Hypospadias was classif...

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Principais autores: Susumu Yamada, Katsumi Miyahara, Naho Fujiwara, Kazuto Suda, Hiroyuki Koga, Geoffrey J. Lane, Atsuyuki Yamataka, Go Miyano, Manabu Okawada
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-04-01
Serier:Journal of Pediatric Surgery Open
Fag:
Hypospadias
Fibroblast growth factors (FGF)
Immunohistochemistry
Western blotting
Online adgang:http://www.sciencedirect.com/science/article/pii/S2949711625000152
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