Inhibitory Effect of ATP on Cytochrome c Oxidase Depends on Electron Entry Pathways by TCA Cycle Metabolites

The ATP-dependent inhibition of cytochrome c oxidase (CytOx, complex IV of the electron transport chain) is the second mechanism of respiratory control adjusting mitochondrial respiration in order to prevent excessive electron flow and reactive oxygen species (ROS) production. Here, we investigate h...

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Autors principals:	Madeline Günther, Valeria Pakic, Petra Weber, Anke Veit, Carsten Culmsee, Ardawan J. Rastan, Annegret P. Busch, Sebastian Vogt
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2026-04-01
Col·lecció:	Cells
Matèries:	cytochrome c oxidase ATP-dependent inhibition respiratory control TCA cycle metabolites complex I and II mitochondrial ROS
Accés en línia:	https://www.mdpi.com/2073-4409/15/9/811
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