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Capicua regulates proliferation and survival of RB-deficient cells in Drosophila

Summary Mutations in rbf1, the Drosophila homologue of the RB tumour suppressor gene, generate defects in cell cycle control, cell death, and differentiation during development. Previous studies have established that EGFR/Ras activity is an important determinant of proliferation and survival in rbf1...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Kate Krivy, Mary-Rose Bradley-Gill, Nam-Sung Moon
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2012-11-01
Schriftenreihe:Biology Open
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Online-Zugang:http://bio.biologists.org/content/2/2/183
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