The role of high mobility group box 1 (HMGB1) in the pathogenesis of kidney diseases

High mobility group box 1 (HMGB1) is a nuclear protein that can bind to DNA and act as a co-factor for gene transcription. When released into extracellular fluid, it plays a proinflammatory role by acting as a damage-associated molecular pattern molecule (DAMP) (also known as an alarmin) to initiate...

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Detalhes bibliográficos

Principais autores:	Qingjie Chen, Xiaofeng Guan, Xiaocong Zuo, Jianglin Wang, Wenjun Yin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2016-05-01
coleção:	Acta Pharmaceutica Sinica B
Assuntos:	High mobility group box 1 Inflammation Acute kidney injury Chronic kidney disease Diabetic nephropathy Antineutrophil cytoplasmic autoantibody-associated vasculitis Clear cell renal cell carcinoma Nephritis
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211383515300551
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