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Sustained expression of HeyL is critical for the proliferation of muscle stem cells in overloaded muscle

In overloaded and regenerating muscle, the generation of new myonuclei depends on muscle satellite cells (MuSCs). Because MuSC behaviors in these two environments have not been considered separately, MuSC behaviors in overloaded muscle remain unexamined. Here, we show that most MuSCs in overloaded m...

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Autori principali: Sumiaki Fukuda, Akihiro Kaneshige, Takayuki Kaji, Yu-taro Noguchi, Yusei Takemoto, Lidan Zhang, Kazutake Tsujikawa, Hiroki Kokubo, Akiyoshi Uezumi, Kazumitsu Maehara, Akihito Harada, Yasuyuki Ohkawa, So-ichiro Fukada
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications Ltd 2019-09-01
Serie:eLife
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Accesso online:https://elifesciences.org/articles/48284
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