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PLCζ Induced Ca2+ Oscillations in Mouse Eggs Involve a Positive Feedback Cycle of Ca2+ Induced InsP3 Formation From Cytoplasmic PIP2

Egg activation at fertilization in mammalian eggs is caused by a series of transient increases in the cytosolic free Ca2+ concentration, referred to as Ca2+ oscillations. It is widely accepted that these Ca2+ oscillations are initiated by a sperm derived phospholipase C isoform, PLCζ that hydrolyses...

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Váldodahkkit: Jessica R. Sanders, Bethany Ashley, Anna Moon, Thomas E. Woolley, Karl Swann
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2018-04-01
Ráidu:Frontiers in Cell and Developmental Biology
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Liŋkkat:http://journal.frontiersin.org/article/10.3389/fcell.2018.00036/full
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