Curcumin Inhibits the Proteinase-Activated Receptor-2–Triggered Prostaglandin E2 Production by Suppressing Cyclooxygenase-2 Upregulation and Akt-Dependent Activation of Nuclear Factor-κB in Human Lung Epithelial Cells

We performed this study to determine if curcumin affects pro-inflammatory responses to activation of proteinase-activated receptor-2 (PAR2) in human pulmonary adenocarcinoma A549 cells. Curcumin completely inhibited the PAR2-triggered prostaglandin E2 (PGE2) production, but notably not interleukin-8...

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Ngā kaituhi matua:	Kazumi Moriyuki, Fumiko Sekiguchi, Kaori Matsubara, Hiroyuki Nishikawa, Atsufumi Kawabata
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Elsevier 2010-01-01
Rangatū:	Journal of Pharmacological Sciences
Urunga tuihono:	http://www.sciencedirect.com/science/article/pii/S1347861319308631
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!