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OncomiR-181a promotes carcinogenesis by repressing the extracellular matrix proteoglycan decorin in hepatocellular carcinoma

Abstract Background Proteoglycans are important tumor microenvironment extracellular matrix components. The regulation of key proteoglycans, such as decorin (DCN), by miRNAs has drawn attention since they have surfaced as novel therapeutic targets in cancer. Accordingly, this study aimed at identify...

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Detalhes bibliográficos
Principais autores: Reem Amr Assal, Rowan Bahaa El-din Abd El-bary, Rana A. Youness, Mohamed Mamdouh Abdelrahman, Hala Zahran, Karim Adel Hosny, Gamal Esmat, Kai Breuhahn, Nada El-Ekiaby, Injie Omar Fawzy, Ahmed Ihab Abdelaziz
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-09-01
coleção:BMC Gastroenterology
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Acesso em linha:https://doi.org/10.1186/s12876-024-03413-6
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