HNF4α inhibits the malignancy of intrahepatic cholangiocarcinoma by suppressing the Wnt signaling pathway

Previous studies have demonstrated that intrahepatic cholangiocarcinoma (ICC) may derive from transdifferentiation of hepatocytes, so transforming ICC cells into hepatocytes could be a potential strategy for treating ICC. Hepatocyte nuclear factor 4α (HNF4α), a master transcription factor in the liv...

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Autors principals:	Bo-Nan Xu, Cheng-Hong Ding, Yi-Long Liu, Yuan-Yuan Luo, Juan Deng, Shu-Qing Liu, Meng-Chao Xiao, Nan Jiang, Xin Zhang, Wen-Ping Xu, Wei-Fen Xie
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2025-03-01
Col·lecció:	Translational Oncology
Matèries:	Hepatocyte nuclear factor 4α (HNF4α) Intrahepatic cholangiocarcinoma (ICC) Wnt signaling pathway Isocitrate dehydrogenase 1(IDH1)
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S193652332500021X
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