Mismatch Repair Deficiency and Microsatellite Instability
Mismatch repair deficiency (MMRd) is caused by the biallelic inactivation of an MMR gene, which can be attributed either to an inherited or an acquired pathway. MMRd is characterized by the inability of cells to repair spontaneous mutations in microsatellites that occur during replication. Microsate...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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MDPI AG
2022-08-01
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| Series: | Encyclopedia |
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| Acceso en liña: | https://www.mdpi.com/2673-8392/2/3/106 |
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