Increased UHMWPE Particle-Induced Osteolysis in Fetuin-A-Deficient Mice

Particle-induced osteolysis is a major cause of aseptic prosthetic loosening. Implant wear particles stimulate tissue macrophages inducing an aseptic inflammatory reaction, which ultimately results in bone loss. Fetuin-A is a key regulator of calcified matrix metabolism and an acute phase protein. W...

Fuld beskrivelse

Bibliografiske detaljer

Principais autores:	Christina Polan, Christina Brenner, Monika Herten, Gero Hilken, Florian Grabellus, Heinz-Lothar Meyer, Manuel Burggraf, Marcel Dudda, Willi Jahnen-Dechent, Christian Wedemeyer, Max Daniel Kauther
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2023-01-01
Serier:	Journal of Functional Biomaterials
Fag:	implants arthroplasty aseptic prosthetic loosening osteolysis particle-induced osteolysis mouse calvaria osteolysis model
Online adgang:	https://www.mdpi.com/2079-4983/14/1/30
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!