Delving into the significance of the His289Tyr single-nucleotide polymorphism in the glutamate ionotropic receptor kainate-1 (Grik1) gene of a genetically audiogenic seizure model

Genetic abnormalities affecting glutamate receptors are central to excitatory overload-driven neuronal mechanisms that culminate in seizures, making them pivotal targets in epilepsy research. Increasingly used to advance this field, the genetically audiogenic seizure hamster from Salamanca (GASH/Sal...

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Detalhes bibliográficos

Principais autores:	Sandra M. Díaz-Rodríguez, M. Javier Herrero-Turrión, Carlos García-Peral, Ricardo Gómez-Nieto
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2024-01-01
coleção:	Frontiers in Molecular Neuroscience
Assuntos:	animal models of epilepsy GASH/Sal GluK1 glutamatergic system kainate receptor neurotransmission
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fnmol.2023.1322750/full
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