Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis

Summary: The fungal pathogen Candida albicans is linked to chronic brain diseases such as Alzheimer’s disease (AD), but the molecular basis of brain anti-Candida immunity remains unknown. We show that C. albicans enters the mouse brain from the blood and induces two neuroimmune sensing mechanisms in...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Yifan Wu, Shuqi Du, Lynn H. Bimler, Kelsey E. Mauk, Léa Lortal, Nessim Kichik, James S. Griffiths, Radim Osicka, Lizhen Song, Katherine Polsky, Lydia Kasper, Peter Sebo, Jill Weatherhead, J. Morgan Knight, Farrah Kheradmand, Hui Zheng, Jonathan P. Richardson, Bernhard Hube, Julian R. Naglik, David B. Corry
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2023-10-01
Schriftenreihe:	Cell Reports
Schlagworte:	CP: Neuroscience CP: Immunology
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2211124723012524
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!