Spermine accumulation via spermine synthase promotes tumor cell proliferation in head and neck squamous cell carcinoma

Abstract Background Head and neck squamous cell carcinoma (HNSCC) is among the most aggressive malignancies, underscoring the need for early diagnosis to improve patient outcomes. Tumor-derived exosomes, which can be non-invasively obtained and reflect the metabolic state of tumors in real-time, are...

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Autors principals:	Xi Chen, Fei Song, Peng Xiao, Yisong Yao, Dongxian Li, Yuhui Fang, Shijun Lv, Yakui Mou, Yumei Li, Xicheng Song
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-03-01
Col·lecció:	BMC Cancer
Matèries:	HNSCC Spermine synthase Metabolomics Liquid chromatography–mass spectrometry Diagnostic biomarkers Tumor metabolism
Accés en línia:	https://doi.org/10.1186/s12885-025-13820-x
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