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The potential therapeutic role of itaconate and mesaconate on the detrimental effects of LPS-induced neuroinflammation in the brain

Abstract Despite advances in antimicrobial and anti-inflammatory treatment, inflammation and its consequences remain a major challenge in the field of medicine. Inflammatory reactions can lead to life-threatening conditions such as septic shock, while chronic inflammation has the potential to worsen...

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Autors principals: Melanie Ohm, Shirin Hosseini, Niklas Lonnemann, Wei He, Tushar More, Oliver Goldmann, Eva Medina, Karsten Hiller, Martin Korte
Format: Artigo
Idioma:Inglês
Publicat: BMC 2024-08-01
Col·lecció:Journal of Neuroinflammation
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Accés en línia:https://doi.org/10.1186/s12974-024-03188-3
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