3D chromatin interactions involving Drosophila insulators are infrequent but preferential and arise before TADs and transcription
Abstract In mammals, insulators contribute to the regulation of loop extrusion to organize chromatin into topologically associating domains. In Drosophila the role of insulators in 3D genome organization is, however, under current debate. Here, we addressed this question by combining bioinformatics...
Gardado en:
| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2023-10-01
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| Series: | Nature Communications |
| Acceso en liña: | https://doi.org/10.1038/s41467-023-42485-y |
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