MicroRNA-Mediated Direct Reprogramming of Human Adult Fibroblasts Toward Cardiac Phenotype

Modulation of microRNA expression holds the promise to achieve direct reprogramming of fibroblasts into cardiomyocyte-like cells as a new strategy for myocardial regeneration after ischemic heart disease. Previous reports have shown that murine fibroblasts can be directly reprogrammed into induced c...

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Hlavní autoři:	C. Paoletti, C. Divieto, G. Tarricone, F. Di Meglio, D. Nurzynska, V. Chiono
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2020-06-01
Edice:	Frontiers in Bioengineering and Biotechnology
Témata:	cardiac fibroblasts direct reprogramming cardiomyocytes microRNAs digital droplet PCR (ddPCR)
On-line přístup:	https://www.frontiersin.org/article/10.3389/fbioe.2020.00529/full
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