The protein arginine methyltransferase PRMT1 promotes TBK1 activation through asymmetric arginine methylation

Summary: TBK1 is an essential kinase for the innate immune response against viral infection. However, the key molecular mechanisms regulating the TBK1 activation remain elusive. Here, we identify PRMT1, a type I protein arginine methyltransferase, as an essential regulator of TBK1 activation. PRMT1...

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Bibliografiska uppgifter

Huvudupphov:	Zhenzhen Yan, Haifeng Wu, Hansen Liu, Guimin Zhao, Honghai Zhang, Wanxin Zhuang, Feng Liu, Yi Zheng, Bingyu Liu, Lei Zhang, Chengjiang Gao
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Elsevier 2021-09-01
Serie:	Cell Reports
Ämnen:	protein arginine methylation innate antiviral immunity PRMT1 TBK1
Länkar:	http://www.sciencedirect.com/science/article/pii/S2211124721011803
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