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Succinylation: A Functional Nexus Between Metabolic Reprogramming and Epigenetic Modifications in Cancer

Metabolic reprogramming and epigenetic remodeling are critical features of tumorigenesis. The process of metabolic reprogramming causes metabolites like Succinyl-CoA to accumulate. Succinylation, which depends on succinyl-CoA as the direct donor group, plays a crucial role in regulating cancer metab...

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Principais autores: Dan Liu, Runtian Li, Mingzhu Li, Fang Xu, Ying Liang, Yang Sun
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2026-02-01
Serier:Molecules
Fag:
lysine succinylation
succinyl-CoA
metabolic reprogramming
epigenetic modification
cancer
Online adgang:https://www.mdpi.com/1420-3049/31/5/773
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