Implications of Concurrent <i>IDH1</i> and <i>IDH2</i> Mutations on Survival in Glioma—A Case Report and Systematic Review

Both <i>IDH1</i> (isocitrate dehydrogenase 1) and <i>IDH2</i> (isocitrate dehydrogenase 2) mutations play a vital role in the development of gliomas through disruption of normal cellular metabolic processes. Here we describe a case of a patient with an IDH-mutant astrocytoma, in which both <i>IDH1</...

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Detalhes bibliográficos

Principais autores:	Alexander Yuile, Laveniya Satgunaseelan, Joe Wei, Marina Kastelan, Michael F. Back, Maggie Lee, Heng Wei, Michael E. Buckland, Adrian Lee, Helen R. Wheeler
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-10-01
Colecção:	Current Issues in Molecular Biology
Assuntos:	<i>IDH1</i> <i>IDH2</i> glioma astrocytoma next generation sequencing
Acesso em linha:	https://www.mdpi.com/1467-3045/44/10/348
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