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THE ATAXIA-TELANGIECTASIA MUTATED (ATM) GENE PLAYS A PIVOTAL ROLE IN THE REPAIR OF DNA IN CASES OF MYELODYSPLASTIC NEOPLASM

Myelodysplastic Neoplasm (MDS) is an age-associated neoplasia characterized by frequent epigenetic abnormalities being hypermethylation the most common, frequently associated with transformation to acute myeloid leukemia (AML). DNA repair genes have been constantly downregulated in MDS during progre...

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Autori principali: JVC Goes, LR Sampaio, RTG Oliveira, DP Borges, RDB Dias, CLA Araujo, PRC Passos, HLR Junior, SMM Magalhães, RF Pinheiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2024-10-01
Serie:Hematology, Transfusion and Cell Therapy
Accesso online:http://www.sciencedirect.com/science/article/pii/S2531137924010885
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