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SOCS1 mimetics and antagonists: a complementary approach to positive and negative regulation of immune function

Suppressors of cytokine signaling (SOCS) are inducible intracellular proteins that play essential regulatory roles in both immune and non-immune function. Of the eight known members, SOCS1 and SOCS3 in conjunction with regulatory T cells play key roles in regulation of the immune system. Molecular...

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Hlavní autoři: Chulbul M. Ahmed, Joseph eLarkin, Howard M Johnson
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015-04-01
Edice:Frontiers in Immunology
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On-line přístup:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00183/full
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