क्यूआर कोड

Redirecting RNA splicing by SMAD3 turns TGF-β into a tumor promoter

Transforming growth factor β (TGF-β) is a well-known growth inhibitor of normal epithelial cells, but it is also secreted by solid tumors to promote cancer progression. Our recent discovery of SMAD3-PCBP1 complex with direct RNA-binding properties has shed light on how this conversion is implemented...

पूर्ण विवरण

में बचाया:
मुख्य लेखकों: Veenu Tripathi, Ying E. Zhang
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Taylor & Francis Group 2017-01-01
श्रृंखला:Molecular & Cellular Oncology
विषय:
alternative splicing
emt
metastasis
pcbp1
smad3
tgf-β
ऑनलाइन पहुंच:http://dx.doi.org/10.1080/23723556.2016.1265699
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