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Improved homology modeling of the human & rat EP4 prostanoid receptors

Abstract Background The EP4 prostanoid receptor is one of four GPCRs that mediate the diverse actions of prostaglandin E2 (PGE2). Novel selective EP4 receptor agonists would assist to further elucidate receptor sub-type function and promote development of therapeutics for bone healing, heart failure...

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Principais autores: Melissa C. Holt, Chi S. Ho, M. Inés Morano, Stephen D. Barrett, Adam J. Stein
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2019-08-01
Series:BMC Molecular and Cell Biology
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Acceso en liña:http://link.springer.com/article/10.1186/s12860-019-0212-5
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